Determination of L-borneol Content of Aipian and Its Chemical Composition Variation during Processing
Abstract:Objective:The chemical composition variation of Aipian process intermediates were analyzed and compared with GC-MS,with the aim to standard and normalize the technology characteristic and technical details of Aipian machining process.Methods:Firstly,the chemical compositions of Aifen,Aiyou and Aipian were analyzed by GC-MS,and then the L-borneol content in Aipian samples was determined by GC.Results:Forty eight chemical ingredients including L-borneol,camphor,morillol,β-caryophyllene,and β-pinene were determined from Aiyou.Eleven chemical ingredients including L-borneol,1-(2-hydroxy-4,6-dimethoxyphenyl)-ethanon,1-phenyl-1,3,3-trimethylindane,and thujopsene were determined from Aifen.Four chemical ingredients including L-borneol,camphor,isoborneol and α-pinene were determined from Aipian.The L-borneol content in 13 Aipian samples was ranged from 1.73-1.82 mg·mL-1,and its relative percentage content ranged from 86.50%-91.00%(CV 0.15%).Conclusion:The results indicated not only the chemical compositions varied during the Aipian machining process,but also the relative percentage content of L-borneol,α-pinene,and other chemical compositions changed also during the machining process.And the L-borneol content in 13 Aipian samples indicated those Aipian samples meet the quality requirements of Chinese pharmacopoeia.