基于红外光谱指纹图谱的当归快速鉴别
投稿时间:2018-04-18     点此下载全文
引用本文:李小阳,宫源,裴纹萱,董玲,孙裕,宋学斌,陈建波,王晶娟.基于红外光谱指纹图谱的当归快速鉴别[J].中国现代中药,2018,20(9):1087-1091
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作者中文名作者英文名单位中文名单位英文名E-Mail
李小阳 LI Xiao-yang 北京中医药大学 中药学院,北京102488 School of Chinese Materia Medica,Beijing University of Chinese Medicine,Beijing 102488,China  
宫源 GONG Yuan 黑龙江省肇东市第一中学,黑龙江肇东151100 Zhaodong No.1 Middle School,Zhaodong 151100,China  
裴纹萱 PEI Wen-xuan 北京中医药大学 生命科学学院,北京100029 School of Life Sciences,Beijing University of Chinese Medicine,Beijing 100029,China  
董玲 DONG Ling 北京中医药大学 生命科学学院,北京100029 School of Life Sciences,Beijing University of Chinese Medicine,Beijing 100029,China  
孙裕 SUN Yu 兰州佛慈制药股份有限公司,甘肃兰州730046 Lanzhou Foci Pharmaceutical Co.,Ltd.,Lanzhou 730046,China  
宋学斌 SONG Xue-bin 兰州佛慈制药股份有限公司,甘肃兰州730046 Lanzhou Foci Pharmaceutical Co.,Ltd.,Lanzhou 730046,China  
陈建波 CHEN Jian-bo 北京中医药大学 生命科学学院,北京100029 School of Life Sciences,Beijing University of Chinese Medicine,Beijing 100029,China 陈建波,助理研究员,研究方向:中药分析与质量评价方法;E-mail:chenjianbo@bucm.edu.cn 
王晶娟 WANG Jing-juan 北京中医药大学 中药学院,北京102488 School of Chinese Materia Medica,Beijing University of Chinese Medicine,Beijing 102488,China 王晶娟,副教授,研究方向:中药鉴定与质量评价方法;E-mail:wangjj@bucm.edu.cn 
基金项目:国家中药标准化项目(ZYBZH-Y-GS-10-B)
中文摘要:目的:建立当归药材的红外光谱指纹图谱及其相似度评价指标,提供一种简便、客观、量化、反映整体成分信息的当归质量快速检测方法。方法:本研究利用PerkinElmer Spectrum One傅里叶变换红外光谱仪对59批当归样品进行测定,使用MATLAB v7.0软件对图谱统计分析。结果:选取1800~800 cm-1、1800~1200 cm-1和1200~800 cm-13个波段分别建立当归药材的相关系数识别阈值,可以准确识别正常与异常当归样品。结论:红外光谱指纹图谱相似度评价方法可以作为现有形性指标和化学指标的补充,为实现当归的全程质量控制提供一种高通量、低成本的快速检测手段。
中文关键词:当归  质量评价  红外光谱  指纹图谱  相关系数
 
Rapid Identification of Radix Angelicae Sinensis Based on Infrared Spectroscopic Fingerprint
Abstract:Objective:To establish an infrared spectroscopic fingerprint of Radix Angelicae Sinensis and its similarity evaluation index,and provide a simple,objective and quantitative method to detect the quality of Radix Angelicae Sinensis.Methods:The PerkinElmer Spectrum One Fourier transform infrared spectrometer was used to determine the 59 batches of Radix Angelicae Sinensis,and the MATLAB v7.0 software was used to analyze the map.Results:1800-800 cm-1,1800-1200 cm-1 and 1200-800 cm-1 were selected to establish the identification threshold of the correlation coefficient of Radix Angelicae Sinensis,and the normal and abnormal samples could be accurately identified.Conclusion:The similarity evaluation method of infrared spectroscopic fingerprint can be used as a supplement technique to the existing physical and chemical indexes.It provides a high throughput and low cost rapid detection method for the whole process quality control of Radix Angelicae Sinensis.
keywords:Radix Angelicae Sinensis  quality evaluation  infrared spectroscopy  fingerprints  correlation coefficients
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