人参水煎煮的科学性探索——水煎煮引发人参皂苷化学结构的转化
投稿时间:2018-12-24     点此下载全文
引用本文:杨秀伟,张雷.人参水煎煮的科学性探索——水煎煮引发人参皂苷化学结构的转化[J].中国现代中药,2019,21(8):1009-1015
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作者中文名作者英文名单位中文名单位英文名E-Mail
杨秀伟 YANG Xiu-Wei 北京大学 药学院 天然药物学系/天然药物及仿生药物国家重点实验室,北京100191 State Key Laboratory of Natural and Biomimetic Drugs,Department of Natural Medicines,School of Pharmaceutical Sciences,Peking University,Beijing 100191,China 杨秀伟,教授,博士生导师,研究方向:天然产物化学与药物代谢;Tel:(010)82801569,E-mail:xwyang@bjmu.edu.cn 
张雷 ZHANG Lei 北京大学 药学院 天然药物学系/天然药物及仿生药物国家重点实验室,北京100191 State Key Laboratory of Natural and Biomimetic Drugs,Department of Natural Medicines,School of Pharmaceutical Sciences,Peking University,Beijing 100191,China  
基金项目:国家自然科学基金重点项目(81530097)
中文摘要:目的:研究人参在水煎煮过程中人参皂苷化学结构的转化。方法:在室温条件下用水超声提取人参和回流提取人参,分别得到两种提取物。然后,通过UFLC-MS/MS和与对照品比较分析及鉴定人参皂苷,比较两个提取物人参皂苷的差别。结果:热水回流提取人参,可以得到多种稀有人参皂苷。结论:通过煎煮转化,极性人参皂苷可产生稀有人参皂苷。
中文关键词:人参  人参皂苷  水煎煮转化  极性人参皂苷  稀有人参皂苷
 
Scientific Exploration on Decoction of Ginseng by Water:Decoction Leading to Transformation of Chemical Structure of Ginsenosides
Abstract:Objective:To study the chemical structure transformation of ginsenosides in ginseng during water decoction.Methods:Ginseng was extracted in water by ultrasonic at room temperature and refluxed in water by heat to give both extracts,respectively.Then,ginsenosides were analysed and identified by ultra-fast liquid chromatography coupled with MS/MS method and comparison with standard substances to compare the ginsenoside difference between the two extracts.Results:A variety of rare ginsenosides can be obtained by extracting ginseng on the water decoction.Conclusion:Rare ginsenosides were produced from polar ginsenosides by water decoction-transformation.
keywords:Ginseng  ginsenoside  water decoction-transformation  polar ginsenoside  rare ginsenoside
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