| 基于近红外光谱技术的砂仁提取物混合工艺研究 |
| 投稿时间：2018-12-27 点此下载全文
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| 引用本文：刘燎原,梁志毅,刘丽萍,钟如帆.基于近红外光谱技术的砂仁提取物混合工艺研究[J].中国现代中药,2020,22(1):85-88 |
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| 摘要点击次数: 1056 |
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| 基金项目:广东特支计划科技创业领军人才项目（2017TY04R197）；广东省科协2018年度创新能力提升项目（粤科标【2018】7号） |
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| 中文摘要:目的：采用近红外光谱技术（NIRS）建立砂仁提取物混合物中砂仁挥发油β-环糊精包合物的定量模型，并优化砂仁提取物混合工艺。方法：以砂仁挥发油β-环糊精包合物含量为真实值，运用偏最小二乘（PLS）法建立NIRS与砂仁挥发油β-环糊精包合物含量之间的定量校正模型，并对混合工艺进行优选。结果：所建NIRS定量模型r=0.995 5，交互验证误差均方根（RMSECV）为0.383，验证集平均预测回收率为98.22%，表明该模型预测能力较好；砂仁提取物混合物不同部位中挥发油β-环糊精包合物含量测定的RSD分别为2.48%、3.42%、2.25%，均小于5.0%，表明混合均匀，确定砂仁提取物的混合工艺为：混合转速5 r·min-1，混合时间20 min。结论：NIRS技术可用于砂仁提取物混合工艺的检测与评价。 |
| 中文关键词:近红外光谱 砂仁 挥发油β-环糊精包合物 混合工艺 |
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| Researchon Mixing Process of Amomum Villosum Extract Based on Near Infrared Spectroscopy |
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| Abstract:Objective：To establish a quantitative model of Amomum Villosum volatile oil β-cyclodextrin （β-CD） inclusion compound of Amomum villosum extract mixture by using near infrared spectroscopy (NIRS)，and optimize the mixing process of Amomum villosum extract. Methods：Taking the actual content of Amomum Villosum volatile oil inclusion compound as the true value，the quantitative correction model between NIRS and Amomum Villosum volatile oil β-CD inclusion compound content was established by partial least squares （PLS） method，and the mixing process was optimized.Results：The correlation coefficient （r） of the established NIRS quantitative model was 99.55%，the root mean square （RMSECV） of the interactive verification error was 0.383，and the average prediction recovery rate of the verification set was 98.22%，indicating that the model had good prediction ability.The RSD values of volatile oil β-CD inclusion compounds in different parts of Amomum Villosum extract mixture were 2.48%，3.42% and 2.25% respectively，all less than 5.0%，indicating that when Amomum Villosum extract was mixed at 5 r·min-1，the mixture was almost evenly mixed at 20 min.Conclusion：NIRS technology can be used to detect and evaluate the mixing process of Amomum Villosum extract. |
| keywords:near infrared spectroscopy Amomum Villosum volatile oil β-CD inclusion compound the mixing process |
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