中药配方颗粒与传统饮片制备四物膏的质量对比研究
投稿时间:2019-03-30     点此下载全文
引用本文:曹亚兰,罗艳萍,罗锦杰.中药配方颗粒与传统饮片制备四物膏的质量对比研究[J].中国现代中药,2020,22(1):103-107
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作者中文名作者英文名单位中文名单位英文名E-Mail
曹亚兰 CAO Ya-lan 广东一方制药有限公司,广东佛山528244 Guangdong Yifang Pharmaceutical Co.,Ltd.,Foshan 528244,China  
罗艳萍 LUO Yan-ping 广东一方制药有限公司,广东佛山528244 Guangdong Yifang Pharmaceutical Co.,Ltd.,Foshan 528244,China 罗艳萍,副研究员,研究方向:中药新药、保健食品、功能食品及中药护肤品的开发;Tel:(0757)85609410,E-mail:luoyp@e-fong.com 
罗锦杰 LUO Jing-jie 广东一方制药有限公司,广东佛山528244 Guangdong Yifang Pharmaceutical Co.,Ltd.,Foshan 528244,China  
基金项目:广东省中药配方颗粒企业重点实验室项目(2018B030323004);“广东特支计划”科技创业领军人才项目(2017TY04R197)
中文摘要:目的:对比研究评价中药配方颗粒与传统饮片制备四物膏的质量等效性,探索中药配方颗粒制作四物膏的可行性。方法:采用感官评价、薄层色谱法(TLC)、高效液相色谱法(HPLC)、红外光谱法(IR)等,以感官和阿魏酸、芍药苷、毛蕊花糖苷等含量为评价指标,对不同原料制备的四物膏进行定性定量分析。结果:2种四物膏产品在外观、化学成分、含量方面无明显差异。结论:中药配方颗粒与传统饮片制备四物膏的质量没有明显差别,为中药配方颗粒制备膏滋提供了实验依据。
中文关键词:四物膏  中药配方颗粒  质量对比
 
Comparative Study on Quality of Siwu Paste Made by Formula Granules and Pieces
Abstract:Objective:The quality equivalence between traditional Chinese medicine granule and traditional Chinese decoction pieces was studied and evaluated,and the feasibility of traditional Chinese medicine granule was explored.Methods:Sensory evaluation,thin layer chromatography (TLC),high performance liquid chromatography (HPLC),infrared spectroscopy (IR) and other methods were used.Sensory and ferulic acid,paeoniflorin,mullein glucoside and other contents were used as evaluation indexes to conduct qualitative and quantitative analysis of Siwu paste prepared with different materials.Results:There was no significant difference in appearance,chemical composition and content between the two kinds of Siwu paste products.Conclusion:There was no significant difference in the quality between traditional Chinese medicine granule and traditional Chinese medicine prepared Siwu paste,which provided experimental basis for preparing Siwu paste.
keywords:Siwu paste  Chinese medicine granule  quality comparison
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