LC-MS技术在天然产物黄酮类成分分析中的应用
投稿时间:2019-09-16     点此下载全文
引用本文:牛江涛,曹瑞,司昕蕾,辛二旦,张育贵,张淑娟,李越峰.LC-MS技术在天然产物黄酮类成分分析中的应用[J].中国现代中药,2020,22(9):1576-1579
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作者中文名作者英文名单位中文名单位英文名E-Mail
牛江涛 NIU Jiang-tao 甘肃中医药大学 药学院,甘肃兰州730000 College of Pharmacy,Gansu University of Traditional Chinese Medicine(TCM),Lanzhou 730000,China  
曹瑞 CAO Rui 甘肃中医药大学 药学院,甘肃兰州730000 College of Pharmacy,Gansu University of Traditional Chinese Medicine(TCM),Lanzhou 730000,China  
司昕蕾 SI Xin-lei 甘肃中医药大学 药学院,甘肃兰州730000 College of Pharmacy,Gansu University of Traditional Chinese Medicine(TCM),Lanzhou 730000,China  
辛二旦 XIN Er-dan 甘肃中医药大学 药学院,甘肃兰州730000 College of Pharmacy,Gansu University of Traditional Chinese Medicine(TCM),Lanzhou 730000,China  
张育贵 ZHANG Yu-gui 甘肃中医药大学 药学院,甘肃兰州730000 College of Pharmacy,Gansu University of Traditional Chinese Medicine(TCM),Lanzhou 730000,China  
张淑娟 ZHANG Shu-juan 甘肃中医药大学 药学院,甘肃兰州730000 College of Pharmacy,Gansu University of Traditional Chinese Medicine(TCM),Lanzhou 730000,China  
李越峰 LI Yue-feng 甘肃中医药大学 药学院,甘肃兰州730000 College of Pharmacy,Gansu University of Traditional Chinese Medicine(TCM),Lanzhou 730000,China 李越峰,教授,研究方向:中药及复方加工炮制机理及活性成分研究;E-mail:lyfyxk@126.comLC-MS 
基金项目:国家自然科学基金项目 (81960713);甘肃省自然科学基金创新基地和人才计划项目(18JR3RA197);甘肃省中药质量与标准研究重点实验室开放基金(ZYZL18-008)
中文摘要:黄酮类化合物是多数植物中的主要成分,并具有广泛的药理活性,因此具有较大的研究价值。目前,国内外学者对黄酮类化合物已做了大量研究,其主要结构、分类、裂解规律等均已有较多报道,液质联用(LC-MS)技术近年来已经成为了黄酮类化合物分析的主要技术和方法。概述LC-MS技术及其分析方法、黄酮类化合物结构特征及其主要裂解方式,并综述了LC-MS技术在黄酮类成分分析中的最新研究,旨在为黄酮类成分的分析测定提供参考。
中文关键词:黄酮类化合物  液质联用技术  结构特征  裂解规律  分析测定
 
Application of LC-MS Technology in Analysis of Flavonoids in Natural Products
Abstract:Flavonoids are the main components in most plants and have a wide range of pharmacological activities,so they have great research value. At present,domestic and foreign scholars have done a lot of research on flavonoids,and the liquid chromatography-mass spectrometry (LC-MS) technology has become the main technology and method for flavonoid analysis in recent years. This paper summarizes the LC-MS technology and its analytical methods,the structural characteristics of flavonoids and its main methods of cleavage,and reviews the recent research on the analysis of flavonoids by LC-MS technology,to provide a reference for the analytical determination of flavonoids.
keywords:flavonoids  LC-MS technique  structural characteristics  cleavage law  analytical determination
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