NMR确定鸡血藤中1个新的降倍半萜类化合物布卢门醇A-6-O-反式-对羟基肉桂酸酯
投稿时间:2020-08-23     点此下载全文
引用本文:杨秀伟,刘晓艳,崔泽旭.NMR确定鸡血藤中1个新的降倍半萜类化合物布卢门醇A-6-O-反式-对羟基肉桂酸酯[J].中国现代中药,2021,23(3):432-436
DOI:
摘要点击次数: 726
全文下载次数: 218
        
作者中文名作者英文名单位中文名单位英文名E-Mail
杨秀伟 YANG Xiu-wei 北京大学 药学院 天然药物学系/天然药物及仿生药物国家重点实验室,北京100191 State Key Laboratory of Natural and Biomimetic Drugs,Department of Natural Medicines,School of Pharmaceutical Sciences,Peking University,Beijing 100191,China 杨秀伟,教授,博士生导师,研究方向:中药有效物质基础和药物代谢;Tel:(010)82801569,E-mail:xwyang@bjmu.edu.cn 
刘晓艳 LIU Xiao-yan 北京大学 药学院 天然药物学系/天然药物及仿生药物国家重点实验室,北京100191 State Key Laboratory of Natural and Biomimetic Drugs,Department of Natural Medicines,School of Pharmaceutical Sciences,Peking University,Beijing 100191,China  
崔泽旭 CUI Ze-xu 北京大学 药学院 天然药物学系/天然药物及仿生药物国家重点实验室,北京100191 State Key Laboratory of Natural and Biomimetic Drugs,Department of Natural Medicines,School of Pharmaceutical Sciences,Peking University,Beijing 100191,China  
基金项目:国家中药标准化项目(ZYBZH-C-HUN-21)
中文摘要:目的:研究鸡血藤水提取物中的化学成分。方法:采用硅胶、高效液相等柱色谱方法进行分离纯化,通过化合物的核磁共振(NMR)数据鉴定其结构。结果:从鸡血藤水提取物中分离出1个降倍半萜类化合物,根据其NMR数据鉴定其化学结构为布卢门醇A-6-O-反式-对羟基肉桂酸酯。结论:布卢门醇A-6-O-反式-对羟基肉桂酸酯为1个新的化合物。
中文关键词:鸡血藤  豆科  降倍半萜  布卢门醇A-6-O-反式-对羟基肉桂酸酯
 
Blumenol A-6-O-trans-p-Hydroxycinnamate as a New Norsesquiterpenoid Determined by NMR Method from Spatholobi Caulis
Abstract:Objective:To study the chemical constituents of aqueous extract of Spatholobi Caulis. Methods:The compound was separated and purified by repeated column chromatography on silica gel and high performance liquid chromatography,and the chemical structure was determined by nuclear magnetic resonance (NMR) spectroscopic data analyses. Results:A norsesquiterpenoid compound was obtained. Its chemical structure was identified as blumenol A-6-O-trans-p-hydroxycinnamate. Conclusion:Blumenol A-6-O-trans-p-hydroxycinnamate is a new compound.
keywords:Spatholobi Caulis  Leguminosae  norsesquiterpenoid  blumenol A-6-O-trans-p-hydroxycinnamate
查看全文   查看/发表评论  下载PDF阅读器