北柴胡化学成分及质量控制方法研究进展
投稿时间:2020-03-15     点此下载全文
引用本文:夏召弟,刘霞.北柴胡化学成分及质量控制方法研究进展[J].中国现代中药,2021,23(5):940-949
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作者中文名作者英文名单位中文名单位英文名E-Mail
夏召弟 XIA Zhao-di 山西省中医药研究院,山西太原030012 Institute of Traditional Chinese Medicine of Shanxi Province,Taiyuan 030012,China  
刘霞 LIU Xia 山西省中医药研究院,山西太原030012 Institute of Traditional Chinese Medicine of Shanxi Province,Taiyuan 030012,China 刘霞,主任药师,硕士生导师,研究方向:中药材及中药饮片道地性研究;Tel:(0351)4668091,E-mail:770191058@qq.com 
基金项目:山西省卫生健康委员会科研项目(2018081);山西省应用基础研究计划项目(201901D211528)
中文摘要:北柴胡为伞形科植物柴胡Bupleurum chinense DC.的干燥根。目前,对北柴胡及同属植物的研究不断深入,尤其在化学成分、药理活性和质量控制等方面已取得较多成果。《中华人民共和国药典》2020年版收载柴胡品种只有北柴胡和南柴胡。就目前柴胡市场而言,南柴胡产量较低,北柴胡种植范围较小,而野生资源枯竭,使得柴胡产量很难满足市场需求。因此,一些产量较高的其他柴胡品种被当做替代品使用。虽然人工种植在很大程度上缓解了柴胡的供给需求,但其有效成分的量受产地、种质、栽培技术等影响较大,也会导致质量稳定性差。因此,建立科学、合理、可行的质量评价体系对柴胡属药用植物资源的合理开发利用至关重要。对近年来北柴胡化学成分及质量控制方法的文献进行归纳总结,并分析今后柴胡研究的发展趋势及工作重点,为阐明柴胡属植物作为药材使用的可能性和可靠性提供参考。
中文关键词:北柴胡  化学成分  质量控制  柴胡属  开发利用
 
Research Progress on Chemical Composition and Quality Control Methods of Bupleurum chinense
Abstract:Bupleuri Radix is the dry root of Bupleurum chinense. At present,the research on B.chinense and its homologous plants is deepening,especially in the aspects of chemical composition,pharmacological activity and quality control. The 2020 edition of Chinese Pharmacopoeia contains only B.chinense and B.scorzonerifolium. As far as the current market is concerned,the yield of B.scorzonerifolium is low,the planting range of B.chinense is small,and the wild resources are exhausted,which makes the yield of Bupleuri Radix difficult to meet the market demand. Therefore,some other varieties with higher yield were used as substitutes. Although artificial cultivation alleviates the supply and demand of B. chinense to a great extent,the amount of its effective components is greatly affected by the origin,germplasm and cultivation technology,which also leads to poor quality stability. Therefore,it is very important to establish a scientific,reasonable and feasible quality evaluation system for the rational development and utilization of Bupleuri Radix medicinal plant resources. This paper summarized the literatures on chemical constituents and quality control methods of B. chinense in recent years,and analyzed the development trend and work focus of its research in the future,so as to provide reference for clarifying the possibility and reliability of Bupleuri Radix as medicinal materials.
keywords:Bupleurum chinense DC.  chemical composition  quality control  Bupleurum L.  development and utilization
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