| Abstract:Anoectochilus roxburghii (Wall.) Lindl. (Orchidaceae) is a rare perennial Chinese herbal material mainly distributed in Fujian, Zhejiang, Jiangxi, Guizhou, and Taiwan of China. It is rich in alkaloids, polysaccharides, saponins, flavonoids, esters, volatile oils, etc., and possesses hepatoprotective, anti-tumor, hypolipidemic, hypoglycemic, and anti-oxidative effects. In recent years, A. roxburghii has been proved effective in the treatment of carbon tetrachloride-induced liver injury, alcoholic liver disease, non-alcoholic fatty liver disease, autoimmune hepatitis, chronic hepatitis B, etc. Its hepatoprotective effect is achieved mainly by scavenging free radicals, inhibiting lipid peroxidation, stabilizing cell membrane, reducing hepatocyte degeneration, alleviating inflammatory reaction, and repairing liver injury. The present study aimed to review the progress on the hepatoprotective effect and mechanism of A. roxburghii to provide a reference basis for the scientific and effective application of A. roxburghii for liver protection. |
