基于数据挖掘分析瓜蒌-薤白药对组方应用规律
投稿时间:2019-10-11  修订日期:2020-03-08   点此下载全文
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作者中文名作者英文名单位中文名单位英文名E-Mail
付英恺 fuyingkai 山东中医药大学 Shandong University of Traditional Chinese Medicine 18364165172@163.com 
季旭明* jixuming 浙江中医药大学 Zhejiang Chinese Medical University jixuming724@163.com 
基金项目:山东省中医经典名方协同创新中心课题(2018KFZ03)
中文摘要:目的:基于中医传承辅助平台(v2.5)分析瓜蒌-薤白药对组方应用规律以期对瓜蒌-薤白药对的临床应用及其中成药和相关复方制剂的研究开发提供一定的依据。方法:以中华医典(V5.0)和中国知网为数据库,分别收集临证处方中含瓜蒌-薤白药对的古今典型医案,并录入中医传承辅助平台,对其主治病症及组方规律进行系统分析,并得出结论。结果:共筛选出典型医案120部,其中包括古代医案28部,涉及主治疾病13种,包括胸痹、喘病、心悸、便秘等;涉及主要中药25味(频次≥15),包括半夏、川芎、茯苓、黄芪、丹参、桂枝等。常与瓜蒌-薤白配伍治疗胸痹的核心药物有3种,常与瓜蒌-薤白配伍治疗喘病的核心药物有6种;常与瓜蒌-薤白配伍治疗胸痹痰浊内阻证的药物有4种;常与瓜蒌薤白配合治疗喘病痰湿蕴肺证的药物有3种。结论:含瓜蒌-薤白药对处方主治疾病主要为以胸闷、憋喘为主要表现的心系及肺系疾病;该药对配伍不同药物可治疗不同疾病;本研究可以为瓜蒌-薤白药对的临床应用及中成药和相关复方制剂的研究开发提供理论依据。
中文关键词:中医传承辅助平台  瓜蒌  薤白  药对  组方规律  
 
Composition rule of prescription for Trichosanthes kirilowii Maxim -Allii macrostemi bulbus couplet medicine based on data mining
Abstract:ABSTRACT OBJECTIVE:Based on the TCM inheritance support platform (v2.5), this paper analyzes the application rule of Trichosanthes kirilowii Maxim -Allii macrostemi bulbus couplet medicine in order to the clinical application and the research and development of proprietary Chinese medicine and related compound preparations provide a certain basis.Method:Taking the Chinese Medical Code (V5.0) and the Chinese Knowledge Network as the database, collecting the typical medical records of ancient and modern medicine containing Trichosanthes macrostemon in the prescription of clinical evidence respectively,Input the data into the TCM inheritance support platform.systematically analyzing the main symptoms and prescriptions, and drawing the conclusion. Results:A total of 120 typical medical records were selected, including 28 ancient medical records.Among them, 13 kinds of main diseases are involved.such as thoracicobstruction,syndrome characterized by dyspnea,cardiopalmus,astriction.Main Chinese medicine(frequency≥15)25 flavor,such as Pinellia ternata, Salvia miltiorrhiza, Rhizoma Chuanxiong, Poria cocos, Astragalus miltiorrhiza.There are 3 kinds of core drugs often combined with Trichosanthes kirilowii Maxim -Allii macrostemi bulbus couplet medicine in thoracic obstruction,and 6 kinds of core drugs in syndrome characterized by dyspnea.There are 4 kinds of core medicinal materials commonly used in Chest obstruction and phlegm-stasis syndrome with Trichosanthes kirilowii Maxim -Allii macrostemi bulbus couplet medicine,and 3 kinds of core medicinal materials commonly used in Wheezing syndrome of phlegm-turbid obstruction of lung .Conclusions:the main diseases treated with Trichosanthes kirilowii Maxim -Allii macrostemi bulbus couplet medicine prescription were heart and lung diseases, which were mainly characterized by chest tightness and dyspnea,different diseases can be treated with different drugs.Conclusion:This study can provide a theoretical basis for the clinical application and the research and development of proprietary Chinese medicine and related compound preparations provide of Trichosanthes kirilowii Maxim -Allii macrostemi bulbus couplet medicine .
keywords:inheritance support platform  Trichosanthes kirilowii Maxim  Allii macrostemi bulbus  Couplet medicine  Prescription rule  
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