葶苈子化学成分及药理作用研究进展 |
投稿时间:2020-12-08 修订日期:2021-02-05 点此下载全文
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基金项目:山东省重点研发计划(重大科技创新工程)项目(2018CXGC1305);山东省中医经典名方协同创新中心开放课题(2018KFY02), |
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中文摘要:葶苈子为十字花科植物播娘蒿Descurainia sophia或独行菜Lepidium apetalum的干燥成熟种子,用药历史悠久,在我国南、北方以及北温带其他地区均有分布。现代研究表明,葶苈子中含有强心苷类、硫苷类和异硫氰酸类、黄酮类、苯丙素类、有机酸类以及脂肪油类等多种化学成分,具有改善心血管功能、细胞毒活性、止咳祛痰平喘、利尿、改善急性肺损伤和代谢紊乱以及雌激素样作用等药理活性。本文从化学成分及药理作用方面对葶苈子近年来的研究进展进行综述,为其进一步研究及应用提供参考。 |
中文关键词:葶苈子 化学成分 药理作用 |
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Research progress on chemical constituents and pharmacological effects of Tinglizi |
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Abstract:Tinglizi is the dry seed of the cruciferous plant Descurainia Sophia or Lepidium apetalum, which is distributed in south north of China and other areas of the North temperate zone, with a long history of medication. Modern research shows that Tinglizi contains a variety of chemical components such as cardiac glycosides, glucosinolates, isothiocyanates, flavonoids, phenylpropanoids, organic acids, fatty oils, etc., and has pharmacological activities such as improving the function of cardiovascular, cytotoxic activity, relieving cough, expectorating, relieving asthma, diuresis, improving acute lung injury and metabolic disorders and estrogen-like effects. This article reviewed the research progress of chemical constituents and pharmacological effects of Tinglizi in recent years, providing references for its further study and application. |
keywords:Tinglizi chemical constituents pharmacological effects |
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