葶苈子化学成分及药理作用研究进展
投稿时间:2020-12-08  修订日期:2021-02-05   点此下载全文
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作者中文名作者英文名单位中文名单位英文名E-Mail
林雪竹 Lin xuezhu 鲁南制药集团股份有限公司 Lunan Pharmaceutical Group Co,Ltd LinYi 1352060856@qq.com 
李蔚群 Li Weiqun 鲁南制药集团股份有限公司 Lunan Pharmaceutical Group Co,Ltd LinYi wqlee1020@163.com 
关永霞 Guan Yongxia 鲁南制药集团股份有限公司 Lunan Pharmaceutical Group Co,Ltd LinYi jmsgyx@163.com 
张贵民* Zhang Guimin 鲁南制药集团股份有限公司 Lunan Pharmaceutical Group Co,Ltd LinYi lunanzhangguimin@163.com 
基金项目:山东省重点研发计划(重大科技创新工程)项目(2018CXGC1305);山东省中医经典名方协同创新中心开放课题(2018KFY02),
中文摘要:葶苈子为十字花科植物播娘蒿Descurainia sophia或独行菜Lepidium apetalum的干燥成熟种子,用药历史悠久,在我国南、北方以及北温带其他地区均有分布。现代研究表明,葶苈子中含有强心苷类、硫苷类和异硫氰酸类、黄酮类、苯丙素类、有机酸类以及脂肪油类等多种化学成分,具有改善心血管功能、细胞毒活性、止咳祛痰平喘、利尿、改善急性肺损伤和代谢紊乱以及雌激素样作用等药理活性。本文从化学成分及药理作用方面对葶苈子近年来的研究进展进行综述,为其进一步研究及应用提供参考。
中文关键词:葶苈子  化学成分  药理作用
 
Research progress on chemical constituents and pharmacological effects of Tinglizi
Abstract:Tinglizi is the dry seed of the cruciferous plant Descurainia Sophia or Lepidium apetalum, which is distributed in south north of China and other areas of the North temperate zone, with a long history of medication. Modern research shows that Tinglizi contains a variety of chemical components such as cardiac glycosides, glucosinolates, isothiocyanates, flavonoids, phenylpropanoids, organic acids, fatty oils, etc., and has pharmacological activities such as improving the function of cardiovascular, cytotoxic activity, relieving cough, expectorating, relieving asthma, diuresis, improving acute lung injury and metabolic disorders and estrogen-like effects. This article reviewed the research progress of chemical constituents and pharmacological effects of Tinglizi in recent years, providing references for its further study and application.
keywords:Tinglizi  chemical constituents  pharmacological effects
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