对照提取物在中药质量控制中的研究现状及展望
投稿时间:2022-07-20     点此下载全文
引用本文:穆开朗,刘刚,刘育辰,李昌桔,李艳,阮玉兰.对照提取物在中药质量控制中的研究现状及展望[J].中国现代中药,2023,25(4):907-915
DOI:10.13313/j.issn.1673-4890.20220720002
摘要点击次数: 349
全文下载次数: 39
                 
作者中文名作者英文名单位中文名单位英文名E-Mail
穆开朗 MU Kai-lang 贵州中医药大学,贵州 贵阳 550025 Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China  
刘刚 LIU Gang 贵州中医药大学,贵州 贵阳 550025 Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China  
刘育辰* LIU Yu-chen 贵州中医药大学,贵州 贵阳 550025 Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China  
李昌桔 LI Chang-ju 贵州中医药大学,贵州 贵阳 550025 Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China  
李艳 LI Yan 贵州中医药大学,贵州 贵阳 550025 Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China  
阮玉兰 RUAN Yu-lan 贵州中医药大学,贵州 贵阳 550025 Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China  
基金项目:国家自然科学基金项目(81860700);贵州省科技计划项目(黔科合基础〔2019〕1027号)
中文摘要:应用对照提取物进行中药质量控制具有专属性强、成本低,对照提取物易于获取、稳定性佳等优势。目前,对照提取物作为一种标准参照物已被广泛应用于中药质量控制领域。对中药对照提取物的概况、发展及近年来国内外有关其在中药质量控制中的研究现状进行综述。同时,在当前中医药发展的新形势下,针对中药质量控制指标与中药有效性关联不强等系列问题,对中药对照提取物的发展进行展望,强化中药对照提取物与其功效的关联性,初步提出“有效对照提取物”这一可应用于中药质量控制、药品开发等方面的提升概念,以期为中药全面药效物质基础及中药质量控制研究提供参考。
中文关键词:对照提取物  中药质量  有效对照提取物  质量控制  标准物质
 
Status and Outlook of Control Extracts in Quality Control of Chinese Medicine
Abstract:The application of control extracts for quality control of Chinese medicine has many advantages such as high specificity, low cost, easy accessibility, and good stability. Currently, the control extracts have been widely used in the field of quality control of Chinese medicine. In this paper, the overview and development of control extracts in Chinese medicine was reviewed, as well as the current status of research on control extracts in quality control of Chinese medicine in China and abroad in recent years. At the same time, in the new situation of Chinese medicine development, the development of Chinese medicine control extracts was prospected to strengthen the correlation between Chinese medicine control extracts and their efficacy, and the concept of "effective control extracts" was proposed, which was applied to the quality control and drug development of Chinese medicine. This paper is expected to provide references for the research on the material basis of the overall efficacy and quality control of Chinese medicine.
keywords:control extracts  quality of Chinese medicine  effective control extracts  quality control  standard substances
查看全文   查看/发表评论  下载PDF阅读器