| 不同规格平贝母止咳祛痰抗炎的药效研究 |
| 投稿时间：2019-11-15 点此下载全文
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| 引用本文：赵倩,李波,沈莹,孟祥才.不同规格平贝母止咳祛痰抗炎的药效研究[J].中国现代中药,2020,22(9):1475-1477 |
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| 基金项目:2018年中医药公共卫生服务补助专项（财社［2018］43号） |
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| 中文摘要:目的：比较大、中、小粒平贝母止咳、祛痰、抗炎功效，探讨采用大小作为平贝母药材质量评价标准的科学性。方法：采用小鼠氨水引咳法比较不同大小平贝母的止咳作用；采用小鼠气管段酚红排痰法比较祛痰作用；采用小鼠耳廓肿胀法比较抗炎作用。结果：止咳作用中贝母有优于小贝母的趋势；祛痰作用三者效果接近；抗炎作用中贝母有优于小贝母的趋势，但差异均无统计学意义。结论：以平贝母的大小评价药材质量缺乏科学依据。 |
| 中文关键词:平贝母 止咳 祛痰 抗炎 质量评价 |
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| Antitnssive,Expectorant and Antiinflammatory Effeats of Fritillariae Ussuriensis Bulbus |
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| Abstract:Objective：To investigate the rationality of evaluation the quality of the Fritillariae Ussuriensis Bulbus by the size of the bulbs based on the cough，expectorant and anti-inflammatory effects. Methods：The antitussive effect was tested by ammonium hydroxide causing cough method in mice，the sputum effect was observed by tracheal phenol red shedding method in mice，the anti-inflammatory effects was measured by mice ear swelling mehtod. Results：In terms of antitussive，the medium size Fritillariae Ussuriensis Bulbus seemed to show better effect than small size one. In terms of expectoration，they had all similar effect. In terms of anti-inflammatory，the medium size one seeded to show better effect than the small size one. Although there existed a trend，there was no statistical difference. Conclusion：There is no scientific basis for using small size as an index to evaluate the quality of Fritillariae Ussuriensis Bulbus. |
| keywords:Fritillariae Ussuriensis Bulbus antitussive effect expectorant effect anti-inflammatory effects quality evaluation |
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