| 中药治疗神经根型颈椎病作用机制 |
| 投稿时间：2020-12-24 点此下载全文
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| 引用本文：方圣杰,魏戌,唐彬,王旭,李振华,王平,朱立国.中药治疗神经根型颈椎病作用机制[J].中国现代中药,2022,24(5):933-938 |
| DOI：10.13313/j.issn.1673-4890.20201224001 |
| 摘要点击次数: 314 |
| 全文下载次数: 31 |
| 作者中文名 | 作者英文名 | 单位中文名 | 单位英文名 | E-Mail |
| 方圣杰 |
FANG Sheng-jie |
中国中医科学院 望京医院，北京 100102 |
Wang Jing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China |
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| 魏戌* |
WEI Xu |
中国中医科学院 望京医院，北京 100102
中医正骨技术 北京市重点实验室，北京 100700 |
Wang Jing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China
Beijing Key Laboratory of Bone Setting Technology of Traditional Chinese Medicine, Beijing 100700, China |
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| 唐彬 |
TANG Bin |
中国中医科学院 望京医院，北京 100102 |
Wang Jing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China |
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| 王旭 |
WANG Xu |
中国中医科学院 望京医院，北京 100102 |
Wang Jing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China |
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| 李振华 |
LI Zhen-hua |
长春中医药大学 附属医院，吉林 长春 130021 |
The First Affiliated Hospital to Changchun University of Chinese Medicine, Changchun 130021, China |
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| 王平 |
WANG Ping |
天津中医药大学 第一附属医院，天津 300193 |
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China |
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| 朱立国 |
ZHU Li-guo |
中国中医科学院 望京医院，北京 100102
中医正骨技术 北京市重点实验室，北京 100700 |
Wang Jing Hospital, China Academy of Chinese Medical Sciences, Beijing 100102, China
Beijing Key Laboratory of Bone Setting Technology of Traditional Chinese Medicine, Beijing 100700, China |
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| 基金项目:中国中医科学院优秀青年科技人才（创新类）培养专项（ZZ13-YQ-039）；中国中医科学院“十三五”重点领域科研项目（ZZ10-022） |
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| 中文摘要:神经根型颈椎病（cervical radiculopathy，CR）发病率逐年上升。中药治疗CR具有多途径、多靶点的优势，其作用机制成为目前研究的重点。近年来，大量证据表明，中药治疗CR主要通过减轻炎症反应、改善血流状态和延缓颈椎退行性改变3个方面达到治疗作用。基于对中药治疗CR的基础研究文献，进一步总结常用中成药或中药复方对CR的治法、作用靶点和相关通路，旨在阐释中药治疗CR的药效学作用及效应机制，为该病的临床治疗提供参考。 |
| 中文关键词:中药 神经根型颈椎病 作用机制 研究进展 |
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| Review on Mechanism of Treatment of Cervical Radiculopathy with Chinese Medicines |
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| Abstract:Cervical radiculopathy (CR), showing an increasing incidence year by year. Chinese medicines can treat CR via multiple targets and pathways, the mechanism of which has become a hot spot of the current research. Recently, abundant evidence has demonstrated that Chinese medicines mainly treat CR through alleviating inflammation, improving blood flow, and mitigating the degenerative changes of the cervical spine. Based on the basic research papers focusing on the treatment of CR with Chinese medicines, this article summarizes the treatment methods, targets, and related pathways of commonly used Chinese patent medicines or Chinese herbal compound prescriptions, aiming to explain the pharmacodynamic effects and mechanisms of Chinese medicines in the treatment of CR and provide reference for the clinical treatment of this disease. |
| keywords:Chinese medicines cervical radiculopathy mechanism of action research progress |
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