| 基于层次分析-熵权法优选温肺平喘汤的提取工艺 |
| 投稿时间：2023-05-19 点此下载全文
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| 引用本文：王博,王瑞,王佳,吴作敏,于晓涛.基于层次分析-熵权法优选温肺平喘汤的提取工艺[J].中国现代中药,2024,26(2):364-369 |
| DOI：10.13313/j.issn.1673-4890.20230519001 |
| 摘要点击次数: 152 |
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| 作者中文名 | 作者英文名 | 单位中文名 | 单位英文名 | E-Mail |
| 王博 |
WANG Bo |
漯河市中心医院 药学部，河南 漯河 462000
河南省中药制剂与加工中医药重点实验室，河南 漯河 462000 |
Department of Pharmacy, Luohe Central Hospital, Luohe 462000, China
Henan Provincial Key Laboratory of TCM Preparations and Processing, Luohe 462000, China |
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| 王瑞 |
WANG Rui |
漯河市中心医院 药学部，河南 漯河 462000
河南省中药制剂与加工中医药重点实验室，河南 漯河 462000 |
Department of Pharmacy, Luohe Central Hospital, Luohe 462000, China
Henan Provincial Key Laboratory of TCM Preparations and Processing, Luohe 462000, China |
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| 王佳 |
WANG Jia |
漯河市中心医院 药学部，河南 漯河 462000 |
Department of Pharmacy, Luohe Central Hospital, Luohe 462000, China |
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| 吴作敏 |
WU Zuo-min |
漯河市中心医院 药学部，河南 漯河 462000
河南省中药制剂与加工中医药重点实验室，河南 漯河 462000 |
Department of Pharmacy, Luohe Central Hospital, Luohe 462000, China
Henan Provincial Key Laboratory of TCM Preparations and Processing, Luohe 462000, China |
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| 于晓涛* |
YU Xiao-tao |
漯河市中心医院 药学部，河南 漯河 462000
河南省中药制剂与加工中医药重点实验室，河南 漯河 462000 |
Department of Pharmacy, Luohe Central Hospital, Luohe 462000, China
Henan Provincial Key Laboratory of TCM Preparations and Processing, Luohe 462000, China |
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| 基金项目:中央引导地方科技发展专项（漯财预指〔020〕309号）；河南省中医药科研专项（2023ZY3033） |
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| 中文摘要:目的 采用层次分析（AHP）-熵权法（EWM）建立多指标综合评价复方的方法，优化温肺平喘汤的提取工艺。方法 以芍药苷、甘草苷、迷迭香酸、丹酚酸B、甘草酸含量和干浸膏得率为评价指标，采用AHP-EWM确定权重系数，通过L9（34）正交设计考察加水倍量、提取时间、提取次数对温肺平喘汤提取工艺的影响。结果 最佳提取工艺为8倍量水提取3次，每次1 h。结论 优选的提取工艺重复性好、稳定性好、提取率高，适用于温肺平喘汤的标准化生产。 |
| 中文关键词:温肺平喘汤 提取工艺 层次分析-熵权法 丹酚酸B |
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| Optimization of Extraction Process of Wenfei Pingchuan Decoction Based on Analytic Hierarchy Process and Entropy Weight Method |
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| Abstract:Objective The analytic hierarchy process (AHP) and entropy weight method (EWM) was used to establish a multi-index comprehensive evaluation method to optimize the extraction process of Wenfei Pingchuan Decoction.Methods The content of paeoniflorin, liquiritin, rosmarinic acid, salvianolic acid B, glycyrrhizic acid and the yield of dry extract were used as evaluation indexes. The weight coefficient was determined by AHP and EWM. L9(34) orthogonal design was used to investigate the effects of water addition, extraction time and number of extractions on the extraction process of Wenfei Pingchuan Decoction.Results The optimal extraction process was to extract 3 times with 8 times amount of waterfor 1 h each time.Conclusion The optimized extraction condition has good repeatability, stability and high extraction rate, which is suitable for the standardized production of Wenfei Pingchuan Decoction. |
| keywords:Wenfei Pingchuan Decoction extraction process analytic hierarchy process and entropy weight method salvianolic acid B |
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