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作者中文名	作者英文名	单位中文名	单位英文名	E-Mail
黄益清	HUANG Yi-qing	山西中医药大学基础医学院，山西晋中 030619	College of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong 030619, China
温煜杰	WEN Yu-jie	山西中医药大学基础医学院，山西晋中 030619	College of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong 030619, China
郑璐璐	ZHENG Lu-lu	山西中医药大学基础医学院，山西晋中 030619	College of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong 030619, China
张俐敏*	ZHANG Li-min	山西中医药大学基础医学院，山西晋中 030619	College of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong 030619, China

基金项目:山西省社会科学界联合会重点课题（SSKLZDKT2023116）；山西省哲学社会科学规划课题（2022YJ090）；山西中医药大学科技创新能力培育计划项目（2022PY-TH-47）

中文摘要:驻景丸是2023年《古代经典名方目录（第二批）》汉族医药的第40首，出自北宋《太平圣惠方》，由菟丝子、车前子、熟地黄3味药组成，功用补益肝肾、清热明目，主治肝肾亏虚之眼病，为中医眼科临床常用名方。采用文献统计学方法，搜集分析驻景丸的古今文献，共筛选有效古籍数据63条，涉及47部中医古籍。从驻景丸的方源方名、组成剂量、药物基原与炮制、制法用法、主治功效等方面进行系统梳理，总结其方证关键信息。研究发现，驻景丸中菟丝子、车前子、熟地黄的配比为5∶3∶3是采用《太平惠民和剂局方》所载剂量；《黎居士简易方论》首载加减驻景丸，该方的主治范围与原方相仿，但药效更全面有力，历代应用更加频繁；现代医家继续对驻景丸进行化裁，提出驻景丸加减方、通络驻景丸等衍生方，广泛应用于眼科临床，取得良好效果。驻景诸方以滋补肝肾为本，或兼宁心安神，或兼清热利湿，或兼化瘀通络，然其对应的病机根本在于肝肾虚损，导致目力不足、障翳昏花。驻景诸方在老年性眼病、其他老年退行性改变及青少年近视防治方面均有良好的应用前景，后续可开展相关药理研究和制剂研发。

中文关键词:经典名方驻景丸《太平圣惠方》历史沿革方证信息文献考证

Historical Evolution of Classical Prescription Zhujing Pill and Analysis of Its Prescription Information

Abstract:Zhujing Pill is the 40th Chinese medicine of the Han ethnic group included in the Catalogue of Ancient Classic Famous Prescriptions (the Second Batch) [Gu Dai Jing Dian Ming Fang Mu Lu (Di Er Pi)] in 2023. It originates from the Taiping Holy Prescriptions for Universal Relief (Tai Ping Sheng Hui Fang) in the Northern Song Dynasty, and is composed of Semen Cuscutae, Semen Plantaginis and Radix Rhemanniae Praeparata, with the efficacy of tonifying and nourishing liver and kidney, clearing heat, and improving vision. Zhujing Pill is a famous prescription commonly used in ophthalmology of traditional Chinese medicine (TCM) for mainly treating eye diseases of liver and kidney deficiency. Ancient and modern literature on Zhujing Pill was collected and analyzed by bibliometrics, and 63 pieces of valid data were screened out from ancient books, involving 47 ancient TCM books. This paper conducted a systematic sorting of the historical origin, prescription names, composition and dosage, herb origin and processing, preparation and usage, therapeutic efficacy, and other aspects of Zhujing Pill, and summarized its key information. The results showed that the ratio of Semen Cuscutae, Semen Plantaginis and Radix Rhemanniae Praeparata in Zhujing Pill was 5:3:3, which followed the dosage in the Formulary of the Bureau of Taiping People's Welfare Pharmacy (Tai Ping Hui Min He Ji Ju Fang). Modified Zhujing Pill was first recorded in the Li Jushi's Prescriptions (Li Ju Shi Jian Yi Fang Lun), and its indications were similar to those of the original prescription, but with more comprehensive and powerful efficacy, and it was more frequently applied in the past. Modern physicians continued to update Zhujing Pill, and put forward derivative prescriptions such as Zhujing Jiajian Pill and Tongluo Zhujing Pill. They have been widely used in ophthalmology and achieved good curative effect. Zhujing prescriptions were based on tonifying and nourishing liver and kidney, concurrently calming heart and tranquilizing mind, or clearing heat and removing dampness, or dispersing blood stasis and unblocking meridian. However, the pathogenesis lied in liver and kidney deficiency, which caused blurred vision. Zhujing prescriptions had excellent application prospects for age-related eye disease, senile degenerative changes, and myopia of juvenile. Relevant pharmacological studies and the development of Chinese medicine preparations could be carried out in the future.

keywords:classical prescription Zhujing Pill Taiping Holy Prescriptions for Universal Relief (Tai Ping Sheng Hui Fang) historical evolution prescription information literature research

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