| 基于电子舌、GC-IMS技术和人工感官评价对小儿感冒颗粒的气味分析和口感改善研究 |
| 投稿时间：2024-02-27 修订日期：2024-03-29 点此下载全文
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| 中文摘要:目的： 改善小儿感冒颗粒的口感,提高患者用药依从性。方法： 试验采用气相色谱离子迁移谱仪(GC-IMS)技术对小儿感冒颗粒进行气味分析及气味来源确定,采用电子舌分析评价了热浸温度、加水量、矫味剂、贮存期等生产工艺参数对小儿感冒颗粒口感的影响,并结合“排序+评分法(ISEM)”评价体系综合评价矫味剂对小儿感冒颗粒的矫味效果。结果： 通过GC-IMS分析在小儿感冒颗粒中共检测出57个挥发性物质,气味主要来自挥发油、挥发油滤液和热浸液中的有机酸类及部分醛类；电子舌分析结果发现生产工艺中不同参数各中间产品口感上的差别并不影响最终颗粒的口感,结合ISEM评价体系进行人工感官评价,最终得出添加2‰氯化钠矫味可以明显改善小儿感冒颗粒的口感,其口感会随贮存期发生变化。结论： 添加2‰氯化钠矫味能够较好地改善小儿感冒颗粒口感问题,为婴幼儿用药口感改善提供了重要参考价值。 |
| 中文关键词:电子舌 气相色谱离子迁移谱仪(GC-IMS) 小儿感冒颗粒 口感 气味 |
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| Research on improvement of Odor Analysis and Taste Analysis of Xiaoer Ganmao Granules based on Electronic Tongue、GC-IMS Technology and Artificial Sensory Evaluation |
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| Abstract:Objiective： To improve the taste of Xiaoer Ganmao Granules and improve patient compliance with medication. Method： In this experiment, GC-IMS technology was used to analyze the smell of Xiaoer cold particles and determine the source of odor, and electronic tongue analysis was used to evaluate the influence of production process parameters such as hot soaking temperature, water addition, flavoring agent,and storage period on the taste of Xiaoer cold particles. The evaluation system of ISEM was used to comprehensively evaluate the taste correction effect of the flavoring agent on Xiaoer Ganmao Granule. Result： A total of 57 volatile substances were detected in pediatric cold particles through GC-IMS analysis. The odor mainly came from the organic acids and some aldehydes in the volatile oil,volatile oil filtrate and hot dip solution; The difference does not affect the taste of the final Granules. Also accomplish artificial sensory evaluation based on ISEM evaluation system. Finally,it is concluded that the addition of 2‰sodium chloride can significantly improve the taste of the pediatric cold granules, and the taste will change with the storage period.Conclusion： This studies provide great value for improving the taste of Xiaoer Ganmao Granules. |
| keywords:： Electronic tongue GC-IMS Xiaoer ganmao granule Taste Smell |
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